The Misuse of Medications in Nursing Homes
Todd Winking June 9, 2022

As part of its commitment to advance health equity by improving the safety and quality of nursing facility residents and staff, the Biden administration has teamed up with the Centers for Medicare & Medicaid Services (CMS) to investigate the issue of overprescription of antipsychotic medications by hospital physicians in nursing homes. 


According to a recent study by the New York Times, 21% of nursing home residents were taking antipsychotic drugs. Some clinicians believe that physicians bear responsibility for overprescribing, while others think that change will come from more academic research in the scientific community. 


doctor-making-sure-her-patient-taking-medication-2021-09-01-00-25-52-utcStock photo from


CMS has partnered with nursing homes, as well as other federal and state organizations, to discover better ways to use non-pharmacological methods in treating conditions that require medication. 


At BASE10, we utilize proprietary, data-driven technology and software management systems to help clinicians identify medications that may be improperly prescribed, with the goals of deprescribing and adverse event reduction in mind. 


As just one example, we use Pharmacogenomics (PGx) to study how genetic variations can affect a person's response to drugs, and whether they’re likely to experience adverse side effects or receive the proper therapeutic benefit from treatment. 


We make it a priority to use thoroughly-researched evidence to deliver PGx results to the patient’s prescribing physician. In accordance with FDA labelling, CPIC guidelines, and other rigorously researched sources, we’ve created a list of 100+ drug-gene pairs that have pharmacogenetic associations. By incorporating PGx into our MTM platform, the patient’s pharmacist is then able to discuss both genetic and nongenetic findings with the prescribing physician to make sure their patients get the best possible care. 


This high-touch clinical engagement platform delivers applicable PGx results as well as non-genetics-informed clinical interventions directly to the patient’s care team, utilizing a cost-effective and time-sensitive method that aims to reduce morbidity, mortality, and costs associated with the “one-size-fits-all” approach to disease treatment and prevention. 







Sign up and join us for BASE10’s upcoming webinar on Thursday, July 28th at 1PM CST: “Understanding Cardiovascular Disease Through a Different Lens with Precision Medicine.”


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About BASE10 Genetics
Located in Chicago, BASE10 is a healthcare software technology company whose platform creates turnkey disease management programs that can be deployed at scale for nursing home operators, pharmacies, payors, and self-funded employers. 


Base10 genetics
Infection management
Precision nutrition
Infection control
Infectious disease
Precision medicine
Long-term care
Nursing home
Skilled nursing facility